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Superantigen-Producing Staphylococcus aureus Elicits Systemic Immune Activation in a Murine Wound Colonization Model

Staphylococcus aureus, the most common cause of wound infection, produces several exotoxins, including superantigens (SAgs). SAgs are the potent activators of the immune system. Given this unique property, we hypothesized that SAgs produced by S. aureus in wounds would have local, as well as systemi...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Kim, Choon K., Karau, Melissa J., Greenwood-Quaintance, Kerryl E., Tilahun, Ashenafi Y., Krogman, Ashton, David, Chella S., Pritt, Bobbi S., Patel, Robin, Rajagopalan, Govindarajan
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690136/
https://ncbi.nlm.nih.gov/pubmed/26670252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins7124886
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