Detection of carcinogenic etheno-DNA adducts in children and adolescents with non-alcoholic steatohepatitis (NASH)

BACKGROUND: Carcinogenic exocyclic-DNA adducts like 1,N(6)-etheno-2'-deoxyadenosine (εdA) are formed through reactive intermediates of 4-hydroxynonenal (4-HNE) or other lipid peroxidation (LPO) products with the DNA bases A, C, methyl-C and G. High levels of hepatic etheno-DNA adducts have been...

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Dades bibliogràfiques
Publicat a:Hepatobiliary Surg Nutr
Autors principals: Teufel, Ulrike, Peccerella, Teresa, Engelmann, Guido, Bruckner, Thomas, Flechtenmacher, Christa, Millonig, Gunda, Stickel, Felix, Hoffmann, Georg F., Schirmacher, Peter, Mueller, Sebastian, Bartsch, Helmut, Seitz, Helmut K.
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2015
Matèries:
Original Article on Nutriition
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689692/
https://ncbi.nlm.nih.gov/pubmed/26734629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2304-3881.2015.12.03
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