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Trm9-Catalyzed tRNA Modifications Regulate Global Protein Expression by Codon-Biased Translation

Post-transcriptional modifications of transfer RNAs (tRNAs) have long been recognized to play crucial roles in regulating the rate and fidelity of translation. However, the extent to which they determine global protein production remains poorly understood. Here we use quantitative proteomics to show...

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Bibliografski detalji
Izdano u:PLoS Genet
Glavni autori: Deng, Wenjun, Babu, I. Ramesh, Su, Dan, Yin, Shanye, Begley, Thomas J., Dedon, Peter C.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689569/
https://ncbi.nlm.nih.gov/pubmed/26670883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005706
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