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Non-Catalytic RISCs and Kinetics Determine Mammalian siRNA Sub-Cellular Localization
Small interfering RNAs (siRNAs) are fundamental to the regulation of cell function. Much is known about its gene interfering mechanism, but a kinetic description of it is still lacking. Here, we derived a set of reaction-diffusion equations for multiple RNA-induced silencing complex (RISC) pathways...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4689521/ https://ncbi.nlm.nih.gov/pubmed/26699128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143182 |
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