Performance and Value of IFN-Lambda3 and IFN-Lambda4 Genotyping in Patients with Chronic Hepatitis C (CHC) Genotype 2/3 in a Real World Setting

BACKGROUND: SNPs near the interferon lambda (IFNL) 3 gene are predictors for sustained virological response (SVR) in patients with chronic hepatitis C genotype (GT) 1. In addition, a dinucleotide frame shift in ss469415590 was described, which generates IFNL4. In this study, we compared the role of...

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Publicado no:PLoS One
Main Authors: Wiegand, Steffen B., Heidrich, Benjamin, Susser, Simone, Rogalska-Taranta, Magdalena, Petersen, Jörg, Böker, Klaus H. W., Grigorian, Natalia, Link, Ralph, Naumann, Uwe, John, Christine, Lueth, Stefan, Malfertheiner, Peter, Manns, Michael P., Wedemeyer, Heiner, Sarrazin, Christoph, Cornberg, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689517/
https://ncbi.nlm.nih.gov/pubmed/26699619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145622
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