Baseline Serum Osteopontin Levels Predict the Clinical Effectiveness of Tocilizumab but Not Infliximab in Biologic-Naïve Patients with Rheumatoid Arthritis: A Single-Center Prospective Study at 1 Year (the Keio First-Bio Cohort Study)

OBJECTIVE: To explore the baseline predictors of clinical effectiveness after tocilizumab or infliximab treatment in biologic-naïve rheumatoid arthritis patients. METHODS: Consecutive biologic-naïve patients with rheumatoid arthritis initiating infliximab (n = 57) or tocilizumab (n = 70) treatment w...

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Pubblicato in:PLoS One
Autori principali: Izumi, Keisuke, Kaneko, Yuko, Hashizume, Misato, Yoshimoto, Keiko, Takeuchi, Tsutomu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689361/
https://ncbi.nlm.nih.gov/pubmed/26698858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145468
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