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Tim-3 enhances FcεRI-proximal signaling to modulate mast cell activation
T cell (or transmembrane) immunoglobulin and mucin domain protein 3 (Tim-3) has attracted significant attention as a novel immune checkpoint receptor (ICR) on chronically stimulated, often dysfunctional, T cells. Antibodies to Tim-3 can enhance antiviral and antitumor immune responses. Tim-3 is also...
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| Gepubliceerd in: | J Exp Med |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Rockefeller University Press
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4689164/ https://ncbi.nlm.nih.gov/pubmed/26598760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150388 |
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