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Targeting KRAS-mutant non-small cell lung cancer: challenges and opportunities

Oncogenic mutations in Kirsten rat sarcoma viral oncogene homolog (KRAS) occur in 15%–30% of non-small cell lung cancer (NSCLC). However, despite decades of intensive research, there is still no direct KRAS inhibitor with clinically proven efficacy. Considering its association with poor treatment re...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Acta Biochim Biophys Sin (Shanghai)
मुख्य लेखकों: Zhang, Jun, Park, Dongkyoo, Shin, Dong M., Deng, Xingming
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689161/
https://ncbi.nlm.nih.gov/pubmed/26578706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/abbs/gmv118
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