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Strategies to circumvent humoral immunity to adeno-associated viral vectors
INTRODUCTION: Recent success in gene therapy of certain monogenic diseases in the clinic has infused enthusiasm into the continued development of recombinant adeno-associated viral (AAV) vectors as next-generation biologics. However, progress in clinical trials has also highlighted the challenges po...
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| Udgivet i: | Expert Opin Biol Ther |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4689135/ https://ncbi.nlm.nih.gov/pubmed/25985812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.2015.1035645 |
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