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Does statin use have a disease modifying effect in symptomatic knee osteoarthritis? Study protocol for a randomised controlled trial

BACKGROUND: Osteoarthritis (OA) is a major clinical and public health problem, with no current medications approved as having disease modifying effects. HMG-CoA reductase inhibitors, or “statins”, a drug class widely used to prevent cardiovascular events, could potentially affect OA progression via...

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Detalles Bibliográficos
Publicado en:Trials
Main Authors: Wang, Yuanyuan, Tonkin, Andrew, Jones, Graeme, Hill, Catherine, Ding, Changhai, Wluka, Anita E., Forbes, Andrew, Cicuttini, Flavia M.
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688994/
https://ncbi.nlm.nih.gov/pubmed/26700937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-015-1122-2
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