Frequencies distribution of dihydrofolate reductase and dihydropteroate synthetase mutant alleles associated with sulfadoxine–pyrimethamine resistance in Plasmodium falciparum population from Hadhramout Governorate, Yemen

BACKGROUND: Malaria in Yemen is mainly caused by Plasmodium falciparum and 25 % of the population is at high risk. Sulfadoxine–pyrimethamine (SP) had been used as monotherapy against P. falciparum. Emergence of chloroquine resistance led to the shift in anti-malarial treatment policy in Yemen to art...

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Veröffentlicht in:Malar J
Hauptverfasser: Bamaga, Omar A. A., Mahdy, Mohammed A. K., Lim, Yvonne A. L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688959/
https://ncbi.nlm.nih.gov/pubmed/26693691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-1035-2
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