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APC and K-ras gene mutation in aberrant crypt foci of human colon

AIM: To study the genetic alteration in ACF and to define the possibility that ACF may be a very early morphological lesion with molecular changes, and to explore the relationship between ACF and colorectal adenoma even carcinoma. METHODS: DNA from 35 CRC, 15 adenomas, 34 ACF and 10 normal mucus was...

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Publicado en:World J Gastroenterol
Autores principales: Yuan, Ping, Sun, Meng-Hong, Zhang, Jin-Sheng, Zhu, Xiong-Zeng, Shi, Da-Ren
Formato: Artigo
Lenguaje:Inglês
Publicado: Baishideng Publishing Group Inc 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688721/
https://ncbi.nlm.nih.gov/pubmed/11819789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v7.i3.352
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