A critical evaluation of drug delivery from ligand modified nanoparticles: confounding small molecule distribution and efficacy in the central nervous system

In this work, we sought to test how surface modification of poly(lactic-co-glycolic acid) (PLGA) nanoparticles with peptide ligand alters the brain specific delivery of encapsulated molecules. For biodistribution studies, nanoparticles modified with rabies virus glycoprotein (RVG29) were loaded with...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Cook, Rebecca L., Householder, Kyle T., Chung, Eugene P., Prakapenka, Alesia V., DiPerna, Danielle M., Sirianni, Rachael W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688251/
https://ncbi.nlm.nih.gov/pubmed/26471392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.10.013
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados