Th17 cytokines differentiate obesity from obesity-associated type 2 diabetes and promote TNFα production

OBJECTIVE: T cell inflammation plays pivotal roles in obesity-associated type 2 diabetes (T2DM). The identification of dominant sources of T cell inflammation in humans remains a significant gap in understanding disease pathogenesis. We hypothesized that cytokine profiles from circulating T cells id...

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Vydáno v:Obesity (Silver Spring)
Hlavní autoři: Ip, Blanche, Cilfone, Nicholas, Belkina, Anna C., DeFuria, Jason, Jagannathan-Bogdan, Madhumita, Zhu, Min, Kuchibhatla, Ramya, McDonnell, Marie E., Xiao, Qiang, Kepler, Thomas B., Apovian, Caroline M., Lauffenburger, Douglas A., Nikolajczyk, Barbara S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688084/
https://ncbi.nlm.nih.gov/pubmed/26576827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21243
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