Elevated Proinflammatory Cytokine Production by a Skewed T Cell Compartment Requires Monocytes and Promotes Inflammation in Type 2 Diabetes

An appropriate balance between proinflammatory (Th17 and Th1) and anti-inflammatory (regulatory T cells [Tregs] and Th2) subsets of T cells is critical to maintain homeostasis and avoid inflammatory disease. Type 2 diabetes (T2D) is a chronic inflammatory disease promoted by changes in immune cell f...

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Hlavní autoři: Jagannathan-Bogdan, Madhumita, McDonnell, Marie E., Shin, Hyunjin, Rehman, Qasim, Hasturk, Hatice, Apovian, Caroline M., Nikolajczyk, Barbara S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3089774/
https://ncbi.nlm.nih.gov/pubmed/21169542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002615
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