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Novel p75 neurotrophin receptor ligand stabilizes neuronal calcium, preserves mitochondrial movement and protects against HIV associated neuropathogenesis

Human immunodeficiency virus (HIV) rapidly penetrates into the brain and establishes a persistent infection of macrophages/microglia. Activation of these cells by HIV results in the secretion of soluble factors that destabilize neuronal calcium homeostasis, encourage oxidative stress and result in n...

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Bibliografske podrobnosti
izdano v:Exp Neurol
Main Authors: Meeker, Rick B., Poulton, Winona, Clary, Gillian, Schriver, Michael, Longo, Frank M.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688079/
https://ncbi.nlm.nih.gov/pubmed/26424436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.09.012
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