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Variants in GBA, SNCA, and MAPT Influence Parkinson Disease Risk, Age at Onset, and Progression

Multiple genetic variants have been linked to risk of Parkinson disease (PD), but known mutations do not explain a large proportion of the total PD cases. Similarly, multiple loci have been associated with PD risk by Genome-Wide Association Studies (GWAS). The influence that genetic factors confer u...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neurobiol Aging
Prif Awduron: Davis, Albert A., Andruska, Kristin M., Benitez, Bruno A., Racette, Brad A., Perlmutter, Joel S., Cruchaga, Carlos
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688052/
https://ncbi.nlm.nih.gov/pubmed/26601739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.09.014
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