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Variants in GBA, SNCA, and MAPT Influence Parkinson Disease Risk, Age at Onset, and Progression

Multiple genetic variants have been linked to risk of Parkinson disease (PD), but known mutations do not explain a large proportion of the total PD cases. Similarly, multiple loci have been associated with PD risk by Genome-Wide Association Studies (GWAS). The influence that genetic factors confer u...

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Detalhes bibliográficos
Publicado no:Neurobiol Aging
Main Authors: Davis, Albert A., Andruska, Kristin M., Benitez, Bruno A., Racette, Brad A., Perlmutter, Joel S., Cruchaga, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688052/
https://ncbi.nlm.nih.gov/pubmed/26601739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.09.014
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