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Variants in GBA, SNCA, and MAPT Influence Parkinson Disease Risk, Age at Onset, and Progression

Multiple genetic variants have been linked to risk of Parkinson disease (PD), but known mutations do not explain a large proportion of the total PD cases. Similarly, multiple loci have been associated with PD risk by Genome-Wide Association Studies (GWAS). The influence that genetic factors confer u...

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Bibliografische gegevens
Gepubliceerd in:Neurobiol Aging
Hoofdauteurs: Davis, Albert A., Andruska, Kristin M., Benitez, Bruno A., Racette, Brad A., Perlmutter, Joel S., Cruchaga, Carlos
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688052/
https://ncbi.nlm.nih.gov/pubmed/26601739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2015.09.014
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