A Tocotrienol-Enriched Formulation Protects against Radiation-Induced Changes in Cardiac Mitochondria without Modifying Late Cardiac Function or Structure

Radiation-induced heart disease (RIHD) is a common and sometimes severe late side effect of radiation therapy for intrathoracic and chest wall tumors. We have previously shown that local heart irradiation in a rat model caused prolonged changes in mitochondrial respiration and increased susceptibili...

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Veröffentlicht in:Radiat Res
Hauptverfasser: Sridharan, Vijayalakshmi, Tripathi, Preeti, Aykin-Burns, Nukhet, Krager, Kimberly J, Sharma, Sunil K., Moros, Eduardo G., Melnyk, Stepan B., Pavliv, Oleksandra, Hauer-Jensen, Martin, Boerma, Marjan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688041/
https://ncbi.nlm.nih.gov/pubmed/25710576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR13915.1
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