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Effects of Local Heart Irradiation in a Glutathione S-Transferase Alpha 4-Null Mouse Model

Glutathione S-transferase alpha 4 (GSTA4-4) is one of the enzymes responsible for the removal of 4-hydroxynonenal (4-HNE), an electrophilic product of lipid peroxidation in cellular membranes during oxidative stress. 4-HNE is a direct activator of nuclear factor (erythroid-derived 2)-like 2 (Nrf2),...

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Dettagli Bibliografici
Pubblicato in:Radiat Res
Autori principali: Boerma, Marjan, Singh, Preeti, Sridharan, Vijayalakshmi, Tripathi, Preeti, Sharma, Sunil, Singh, Sharda P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4688037/
https://ncbi.nlm.nih.gov/pubmed/26010708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR13979.1
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