Whole-proteome genetic analysis of dependencies in assembly of a vertebrate kinetochore

Kinetochores orchestrate mitotic chromosome segregation. Here, we use quantitative mass spectrometry of mitotic chromosomes isolated from a comprehensive set of chicken DT40 mutants to examine the dependencies of 93 confirmed and putative kinetochore proteins for stable association with chromosomes....

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Samejima, Itaru, Spanos, Christos, Alves, Flavia de Lima, Hori, Tetsuya, Perpelescu, Marinela, Zou, Juan, Rappsilber, Juri, Fukagawa, Tatsuo, Earnshaw, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687880/
https://ncbi.nlm.nih.gov/pubmed/26668330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201508072
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