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Bi-Allelic TCRα or β Recombination Enhances T Cell Development but Is Dispensable for Antigen Responses and Experimental Autoimmune Encephalomyelitis

Dual TCRα-expressing T cells outnumber dual TCRβ-expressing cells by ~10:1. As a result, efforts to understand how dual TCR T cells impact immunity have focused on dual TCRα expression; dual TCRβ expression remains understudied. We recently demonstrated, however, that dual TCRβ expression accelerate...

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Veröffentlicht in:PLoS One
Hauptverfasser: Schuldt, Nathaniel J., Auger, Jennifer L., Hogquist, Kristin A., Binstadt, Bryce A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687847/
https://ncbi.nlm.nih.gov/pubmed/26693713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145762
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