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Protein localisation by electron microscopy reveals the architecture of the yeast spliceosomal B complex

The spliceosome assembles on a pre‐mRNA intron by binding of five snRNPs and numerous proteins, leading to the formation of the pre‐catalytic B complex. While the general morphology of the B complex is known, the spatial arrangement of proteins and snRNP subunits within it remain to be elucidated. T...

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Bibliographic Details
Published in:EMBO J
Main Authors: Rigo, Norbert, Sun, Chengfu, Fabrizio, Patrizia, Kastner, Berthold, Lührmann, Reinhard
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687791/
https://ncbi.nlm.nih.gov/pubmed/26582754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201592022
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