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DKK3 blocked translocation of β‐catenin/EMT induced by hypoxia and improved gemcitabine therapeutic effect in pancreatic cancer Bxpc‐3 cell

The Wnt/β‐catenin signalling pathway is activated in pancreatic cancer initiation and progression. Dickkopf‐related protein 3 (DKK3) is a member of the human Dickkopf family and an antagonist of Wnt ligand activity. However, the function of DKK3 in this pathway in pancreatic cancer is rarely known....

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Détails bibliographiques
Publié dans:J Cell Mol Med
Auteurs principaux: Guo, Qingqu, Qin, Wenjie
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687707/
https://ncbi.nlm.nih.gov/pubmed/26395974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12675
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