Preparation of albumin nanospheres loaded with gemcitabine and their cytotoxicity against BXPC-3 cells in vitro

AIM: To optimize formulation methods for loading gemcitabine (GEM), the main drug against pancreatic cancer, into albumin nanoparticles for extended blood circulation and improved efficacy. METHODS: GEM was loaded into two sizes of disolvation-crosslinked bovine serum albumin nanoparticles, with a m...

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Main Authors: Li, Jin-ming, Chen, Wei, Wang, Hao, Jin, Chen, Yu, Xian-jun, Lu, Wei-yue, Cui, Long, Fu, De-liang, Ni, Quan-xing, Hou, Hui-min
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007180/
https://ncbi.nlm.nih.gov/pubmed/19730429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2009.125
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