The Mediator subunit MED23 couples H2B mono‐ubiquitination to transcriptional control and cell fate determination

The Mediator complex orchestrates multiple transcription factors with the Pol II apparatus for precise transcriptional control. However, its interplay with the surrounding chromatin remains poorly understood. Here, we analyze differential histone modifications between WT and MED23(−/−) (KO) cells an...

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Vydáno v:EMBO J
Hlavní autoři: Yao, Xiao, Tang, Zhanyun, Fu, Xing, Yin, Jingwen, Liang, Yan, Li, Chonghui, Li, Huayun, Tian, Qing, Roeder, Robert G, Wang, Gang
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2015
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687689/
https://ncbi.nlm.nih.gov/pubmed/26330467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591279
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