A non‐canonical role of the p97 complex in RIG‐I antiviral signaling

RIG‐I is a well‐studied sensor of viral RNA that plays a key role in innate immunity. p97 regulates a variety of cellular events such as protein quality control, membrane reassembly, DNA repair, and the cell cycle. Here, we report a new role for p97 with Npl4‐Ufd1 as its cofactor in reducing antivir...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Hao, Qian, Jiao, Shi, Shi, Zhubing, Li, Chuanchuan, Meng, Xia, Zhang, Zhen, Wang, Yanyan, Song, Xiaomin, Wang, Wenjia, Zhang, Rongguang, Zhao, Yun, Wong, Catherine CL, Zhou, Zhaocai
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687688/
https://ncbi.nlm.nih.gov/pubmed/26471729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591888
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