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Structural and Biochemical Insights into the Activation Mechanisms of Germinal Center Kinase OSR1
The oxidative stress-responsive 1 (OSR1) kinase belongs to the mammalian STE20-like kinase family. OSR1 is activated by with no lysine [K] (WNKs) kinases, and then it phosphorylates cation-coupled Cl-cotransporters, regulating ion homeostasis and cell volume in mammalian cells. However, the specific...
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| Yayımlandı: | J Biol Chem |
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| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4276864/ https://ncbi.nlm.nih.gov/pubmed/25389294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.592097 |
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