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Safety and tolerability considerations in the use of sildenafil for children with pulmonary arterial hypertension
Sildenafil is a phosphodiesterase type-5 inhibitor approved for treatment of pulmonary arterial hypertension (PAH) in adults. Data from pediatric trials demonstrate a similar acute safety profile to the adult population but have raised concerns regarding the safety of long-term use in children. Inte...
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| Published in: | Drug Healthc Patient Saf |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Dove Medical Press
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687613/ https://ncbi.nlm.nih.gov/pubmed/26719728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DHPS.S65571 |
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