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Association mapping reveals the role of purifying selection in the maintenance of genomic variation in gene expression
The evolutionary forces that maintain genetic variation in quantitative traits within populations remain poorly understood. One hypothesis suggests that variation is under purifying selection, resulting in an excess of low-frequency variants and a negative correlation between minor allele frequency...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687593/ https://ncbi.nlm.nih.gov/pubmed/26604315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503027112 |
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