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Designer and natural peptide toxin blockers of the KcsA potassium channel identified by phage display
Peptide neurotoxins are powerful tools for research, diagnosis, and treatment of disease. Limiting broader use, most receptors lack an identified toxin that binds with high affinity and specificity. This paper describes isolation of toxins for one such orphan target, KcsA, a potassium channel that h...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687576/ https://ncbi.nlm.nih.gov/pubmed/26627718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1514728112 |
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