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Designer and natural peptide toxin blockers of the KcsA potassium channel identified by phage display
Peptide neurotoxins are powerful tools for research, diagnosis, and treatment of disease. Limiting broader use, most receptors lack an identified toxin that binds with high affinity and specificity. This paper describes isolation of toxins for one such orphan target, KcsA, a potassium channel that h...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687576/ https://ncbi.nlm.nih.gov/pubmed/26627718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1514728112 |
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