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A randomized comparative study to determine the effect of omeprazole on the peak serum concentration of itraconazole oral solution

To determine the effect of omeprazole on peak serum concentrations (C(max)) of itraconazole oral solution (IOS), we carried out a randomized, open-label, prospective, crossover study. Fifteen healthy, non-pregnant adults received a single dose of IOS 400 mg on two occasions, at least 7 days apart, w...

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書誌詳細
出版年:J Antimicrob Chemother
主要な著者: Johnson, Melissa D., Hamilton, Carol D., Drew, Richard H., Sanders, Linda L., Pennick, Gennethel J., Perfect, John R.
フォーマット: Artigo
言語:Inglês
出版事項: 2003
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687480/
https://ncbi.nlm.nih.gov/pubmed/12562722
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