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Concentrations in plasma and safety of 7 days of intravenous itraconazole followed by 2 weeks of oral itraconazole solution in patients in intensive care units.

Pharmacokinetics and safety of a hydroxy-beta-propyl solution of itraconazole were assessed in 16 patients in an intensive care unit. On the first 2 days, four 1-h infusions of 200 mg were given at 0, 8, 24, and 32 h. From day 3 to 7, inclusive, a single 1-h infusion of 200 mg of itraconazole was gi...

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Enregistré dans:
Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Vandewoude, K, Vogelaers, D, Decruyenaere, J, Jaqmin, P, De Beule, K, Van Peer, A, Woestenborghs, R, Groen, K, Colardyn, F
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1997
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC164194/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9420044/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.41.12.2714
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