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Bioassay for serum itraconazole concentrations using hydroxyitraconazole standards.

Low concentrations of itraconazole in serum have been associated with therapeutic failure. Variable interpatient bioavailability and detrimental drug interactions with p450 enzyme-inducing agents are well documented. Thus, routine monitoring of serum itraconazole concentrations in patients with life...

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Bibliographic Details
Main Authors: Law, D, Moore, C B, Denning, D W
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC284593/
https://ncbi.nlm.nih.gov/pubmed/7979289
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