A randomized comparative study to determine the effect of omeprazole on the peak serum concentration of itraconazole oral solution

To determine the effect of omeprazole on peak serum concentrations (C(max)) of itraconazole oral solution (IOS), we carried out a randomized, open-label, prospective, crossover study. Fifteen healthy, non-pregnant adults received a single dose of IOS 400 mg on two occasions, at least 7 days apart, w...

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Udgivet i:J Antimicrob Chemother
Main Authors: Johnson, Melissa D., Hamilton, Carol D., Drew, Richard H., Sanders, Linda L., Pennick, Gennethel J., Perfect, John R.
Format: Artigo
Sprog:Inglês
Udgivet: 2003
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687480/
https://ncbi.nlm.nih.gov/pubmed/12562722
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