A randomized comparative study to determine the effect of omeprazole on the peak serum concentration of itraconazole oral solution

To determine the effect of omeprazole on peak serum concentrations (C(max)) of itraconazole oral solution (IOS), we carried out a randomized, open-label, prospective, crossover study. Fifteen healthy, non-pregnant adults received a single dose of IOS 400 mg on two occasions, at least 7 days apart, w...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Antimicrob Chemother
Prif Awduron: Johnson, Melissa D., Hamilton, Carol D., Drew, Richard H., Sanders, Linda L., Pennick, Gennethel J., Perfect, John R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2003
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687480/
https://ncbi.nlm.nih.gov/pubmed/12562722
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