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Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions
Telomerase helps maintain telomeres by processive synthesis of telomere repeat DNA at their 3′-ends, using an integral telomerase RNA (TER) and telomerase reverse transcriptase (TERT). We report the cryo–electron microscopy structure of Tetrahymena telomerase at ~9 angstrom resolution. In addition t...
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| Veröffentlicht in: | Science |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4687456/ https://ncbi.nlm.nih.gov/pubmed/26472759 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab4070 |
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