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Shared Subunits of Tetrahymena Telomerase Holoenzyme and Replication Protein A Have Different Functions in Different Cellular Complexes

In most eukaryotes, telomere maintenance relies on telomeric repeat synthesis by a reverse transcriptase named telomerase. To synthesize telomeric repeats, the catalytic subunit telomerase reverse transcriptase (TERT) uses the RNA subunit (TER) as a template. In the ciliate Tetrahymena thermophila,...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Upton, Heather E., Chan, Henry, Feigon, Juli, Collins, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217681/
https://ncbi.nlm.nih.gov/pubmed/27895115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.763664
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