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Immunosuppressant MPA Modulates Tight Junction through Epigenetic Activation of MLCK/MLC-2 Pathway via p38MAPK

Background: Mycophenolic acid (MPA) is an important immunosuppressive drug (ISD) prescribed to prevent graft rejection in the organ transplanted patients, however, its use is also associated with adverse side effects like sporadic gastrointestinal (GI) disturbances. Recently, we reported the MPA ind...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Khan, Niamat, Pantakani, D. V. Krishna, Binder, Lutz, Qasim, Muhammad, Asif, Abdul R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687409/
https://ncbi.nlm.nih.gov/pubmed/26733876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00381
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