Immunosuppressant MPA Modulates Tight Junction through Epigenetic Activation of MLCK/MLC-2 Pathway via p38MAPK

Background: Mycophenolic acid (MPA) is an important immunosuppressive drug (ISD) prescribed to prevent graft rejection in the organ transplanted patients, however, its use is also associated with adverse side effects like sporadic gastrointestinal (GI) disturbances. Recently, we reported the MPA ind...

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Dades bibliogràfiques
Publicat a:Front Physiol
Autors principals: Khan, Niamat, Pantakani, D. V. Krishna, Binder, Lutz, Qasim, Muhammad, Asif, Abdul R.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2015
Matèries:
Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687409/
https://ncbi.nlm.nih.gov/pubmed/26733876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00381
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