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Directly interrogating single quantum dot labelled UvrA(2) molecules on DNA tightropes using an optically trapped nanoprobe

In this study we describe a new methodology to physically probe individual complexes formed between proteins and DNA. By combining nanoscale, high speed physical force measurement with sensitive fluorescence imaging we investigate the complex formed between the prokaryotic DNA repair protein UvrA(2)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Simons, Michelle, Pollard, Mark R., Hughes, Craig D., Ward, Andrew D., Van Houten, Bennett, Towrie, Mike, Botchway, Stan W., Parker, Anthony W., Kad, Neil M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686980/
https://ncbi.nlm.nih.gov/pubmed/26691010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18486
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