Competitive allele-specific TaqMan PCR (Cast-PCR) is a sensitive, specific and fast method for BRAF V600 mutation detection in Melanoma patients

BRAF codon 600 mutation testing of melanoma patients is mandatory for the choice of the most appropriate therapy in the clinical setting. Competitive allele specific TaqMan PCR (Cast-PCR) technology allows not only the selective amplification of minor alleles, but it also blocks the amplification of...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Barbano, Raffaela, Pasculli, Barbara, Coco, Michelina, Fontana, Andrea, Copetti, Massimiliano, Rendina, Michelina, Valori, Vanna Maria, Graziano, Paolo, Maiello, Evaristo, Fazio, Vito Michele, Parrella, Paola
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686972/
https://ncbi.nlm.nih.gov/pubmed/26690267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18592
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