Hsa-miR-155-5p Up-Regulation in Breast Cancer and Its Relevance for Treatment With Poly[ADP-Ribose] Polymerase 1 (PARP-1) Inhibitors

miR-155-5p is a well-known oncogenic microRNA, showing frequent overexpression in human malignancies, including breast cancer. Here, we show that high miR-155-5p levels are associated with unfavorable prognostic factors in two independent breast cancer cohorts (CSS cohort, n = 283; and TCGA-BRCA dat...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Pasculli, Barbara, Barbano, Raffaela, Fontana, Andrea, Biagini, Tommaso, Di Viesti, Maria Pia, Rendina, Michelina, Valori, Vanna Maria, Morritti, Maria, Bravaccini, Sara, Ravaioli, Sara, Maiello, Evaristo, Graziano, Paolo, Murgo, Roberto, Copetti, Massimiliano, Mazza, Tommaso, Fazio, Vito Michele, Esteller, Manel, Parrella, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7435065/
https://ncbi.nlm.nih.gov/pubmed/32903519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.01415
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