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Comparative Proteomic Profiling of Ehrlichia ruminantium Pathogenic Strain and Its High-Passaged Attenuated Strain Reveals Virulence and Attenuation-Associated Proteins

The obligate intracellular bacterium Ehrlichia ruminantium (ER) causes heartwater, a fatal tick-borne disease in livestock. In the field, ER strains present different levels of virulence, limiting vaccine efficacy, for which the molecular basis remains unknown. Moreover, there are no genetic tools c...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Marcelino, Isabel, Ventosa, Miguel, Pires, Elisabete, Müller, Markus, Lisacek, Frédérique, Lefrançois, Thierry, Vachiery, Nathalie, Coelho, Ana Varela
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686967/
https://ncbi.nlm.nih.gov/pubmed/26691135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145328
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