Comparative Proteomic Profiling of Ehrlichia ruminantium Pathogenic Strain and Its High-Passaged Attenuated Strain Reveals Virulence and Attenuation-Associated Proteins

The obligate intracellular bacterium Ehrlichia ruminantium (ER) causes heartwater, a fatal tick-borne disease in livestock. In the field, ER strains present different levels of virulence, limiting vaccine efficacy, for which the molecular basis remains unknown. Moreover, there are no genetic tools c...

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Foilsithe in:PLoS One
Main Authors: Marcelino, Isabel, Ventosa, Miguel, Pires, Elisabete, Müller, Markus, Lisacek, Frédérique, Lefrançois, Thierry, Vachiery, Nathalie, Coelho, Ana Varela
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686967/
https://ncbi.nlm.nih.gov/pubmed/26691135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145328
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