Comparative Proteomic Profiling of Ehrlichia ruminantium Pathogenic Strain and Its High-Passaged Attenuated Strain Reveals Virulence and Attenuation-Associated Proteins

The obligate intracellular bacterium Ehrlichia ruminantium (ER) causes heartwater, a fatal tick-borne disease in livestock. In the field, ER strains present different levels of virulence, limiting vaccine efficacy, for which the molecular basis remains unknown. Moreover, there are no genetic tools c...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Marcelino, Isabel, Ventosa, Miguel, Pires, Elisabete, Müller, Markus, Lisacek, Frédérique, Lefrançois, Thierry, Vachiery, Nathalie, Coelho, Ana Varela
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686967/
https://ncbi.nlm.nih.gov/pubmed/26691135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145328
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