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Identification of miRNAs Involved in Reprogramming Acinar Cells into Insulin Producing Cells

Reprogramming acinar cells into insulin producing cells using adenoviral (Ad)-mediated delivery of Pdx1, Ngn3 and MafA (PNM) is an innovative approach for the treatment of diabetes. Here, we aimed to investigate the molecular mechanisms involved in this process and in particular, the role of microRN...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Teichenne, Joan, Morró, Meritxell, Casellas, Alba, Jimenez, Veronica, Tellez, Noelia, Leger, Adrien, Bosch, Fatima, Ayuso, Eduard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686894/
https://ncbi.nlm.nih.gov/pubmed/26690959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145116
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