miR-34 miRNAs provide a barrier for somatic cell reprogramming

Somatic reprogramming induced by defined transcription factors is a low efficiency process that is enhanced by p53 deficiency (1-5). To date, p21 is the only p53 target shown to contribute to p53 repression of iPSC (induced pluripotent stem cell) generation (1, 3), suggesting additional p53 targets...

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Detalhes bibliográficos
Main Authors: Choi, Yong Jin, Lin, Chao-Po, Ho, Jaclyn J., He, Xingyue, Okada, Nobuhiro, Bu, Pengcheng, Zhong, Yingchao, Kim, Sang Yong, Bennett, Margaux J., Chen, Caifu, Ozturk, Arzu, Hicks, Geoffrey G., Hannon, Greg J., He, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541684/
https://ncbi.nlm.nih.gov/pubmed/22020437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2366
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