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Non-random fragmentation patterns in circulating cell-free DNA reflect epigenetic regulation

BACKGROUND: The assessment of cell-free circulating DNA fragments, also known as a "liquid biopsy" of the patient's plasma, is an important source for the discovery and subsequent non-invasive monitoring of cancer and other pathological conditions. Although the nucleosome-guided fragm...

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Bibliografiske detaljer
Udgivet i:BMC Genomics
Main Authors: Ivanov, Maxim, Baranova, Ancha, Butler, Timothy, Spellman, Paul, Mileyko, Vladislav
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686799/
https://ncbi.nlm.nih.gov/pubmed/26693644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-16-S13-S1
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